NCLEX-RN Oncology & Immunosuppressant Medications Flashcards

A nurse discovers a chemotherapy bag has leaked onto the floor. What is the priority action?

Which medication is administered with Methotrexate to protect healthy cells, and which major organ toxicity requires monitoring?

Complete the statement regarding Cyclophosphamide (Cytoxan) safety:

What is the primary dose-limiting toxicity associated with Doxorubicin (Adriamycin)?

Name the two priority system toxicities associated with Cisplatin therapy.

A client receiving Vincristine reports difficulty buttoning their shirt and numbness in their feet. What complication does this indicate?

Tamoxifen is used to treat breast cancer, but it increases the risk of which secondary cancer?

Complete the definition regarding chemotherapy cycles:

Which laboratory findings indicate Tumor Lysis Syndrome (TLS) in a patient undergoing chemotherapy?

Order the immediate nursing actions for a suspected chemotherapy extravasation (leakage into tissue).

Select the correct monitoring parameters for cyclosporine:

A client taking cyclosporine asks if they can drink grapefruit juice. Which response by the nurse is appropriate?

What are the two major adverse effects of tacrolimus that require monitoring?

What is the primary contraindication for mycophenolate regarding pregnancy, and what is the most common side effect?

A client on long-term immunosuppressant therapy asks about vaccinations. Which statement indicates the client understands the teaching?

What is the priority adverse event to monitor for during a patient's first infusion of Rituximab?

A nurse is preparing to administer rituximab. Which premedication protocol is most appropriate to prevent infusion reactions?

What specific organ toxicity is the primary concern with Trastuzumab (Herceptin) therapy, and what baseline diagnostic is required?

Complete the precaution regarding Trastuzumab drug interactions:

What is the primary mechanism of action (MOA) of checkpoint inhibitors like nivolumab and pembrolizumab?

Which group of adverse effects is most characteristic of immune checkpoint inhibitors, distinguishing them from traditional chemotherapy?

Select the correct interventions for managing immune-related adverse effects:

What 4 specific signs/symptoms should a nurse teach a patient on checkpoint inhibitors to report immediately?

Which screening is the priority before initiating therapy with adalimumab (Humira)?

Select the correct risk and nursing action regarding Tumor Necrosis Factor (TNF) inhibitors.

What are the administration route and storage requirements for adalimumab?

What is the most common cluster of side effects experienced by clients starting interferon therapy?

Which laboratory values and psychological assessments are priorities for a client receiving interferon beta?

What is the primary therapeutic indication for filgrastim?

A client receiving filgrastim reports 'aching pain deep in the lower back and legs.' Which nursing action is appropriate?

Select the correct monitoring parameters for filgrastim therapy:

A client is scheduled to receive chemotherapy at 10:00 AM on Monday. When is the safest time to administer a dose of filgrastim?

What is the primary risk associated with epoetin alfa if the hemoglobin rises too rapidly or exceeds the target range (e.g., >11 g/dL)?